The influence of lemongrass essential oil addition into heat cured acrylic resin against Candida albicans adhesion

Main Article Content

Seineen S Al-Shammari
Faiza M Abdul-Ameer
https://orcid.org/0000-0001-8841-5857
Latifa R Bairam
https://orcid.org/0009-0002-4790-937X
Zeina Al-Salihi
https://orcid.org/0009-0009-2554-2301

Abstract

Background: For decades, the use of naturally accessible materials in treating human disease has been widespread. The goal of this study was to determine the anti-fungal effectiveness /of the lemongrass essential oil (LGEO) versus Candida albicans (C. albicans) adhesion to polymethylmethacrylate (PMMA) materials. Material and methods: LGEO's anti-fungal activity was tested against C. albicans adhesion using the following concentration of LGEO in PMMA monomer (2.5 vol. %, 5 vol. % LGEO) selected from the pilot study as the best two effective concentrations. A total of 40 specimens were fabricated for the candida adherence test and were subdivided into four equal groups: negative control 0 vol. % addition, experimental with 2.5 vol. % and 5 vol. % of LGEO addition and positive control with 1.4 wt. % nystatin addition. The sterile PMMA specimens were incubated at room temperature for 1 hr in sterile tubes with a sabouraud dextrose broth (SDA) in which a small amount of the yeast was isolated and suspended; under the inverted light microscope, the examination was done. The data were evaluated using a one-way ANOVA test, which showed a significant result at p< 0.05. Results: The findings of the C. albicans adherence test exposed a considerable reduction in the number of C. albicans cells adhering to PMMA after adding 2.5 vol. % and 5 vol. % LGEO compared to specimens from the negative control and positive control groups at p< 0.05. Conclusion: Adding LGEO into a heat-cure acrylic material can result in a denture base material with anti-fungal properties versus C. albicans microorganisms. The experimental group 5 vol. % LGEO additive showed the best anti-fungal activity

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Author Biographies

Seineen S Al-Shammari, Department of.Prosthodontics Dentistry, College of Dentistry, University of Baghdad, Baghdad, Iraq

Department of.Prosthodontics Dentistry, College of Dentistry, University of Baghdad, Baghdad, Iraq

Faiza M Abdul-Ameer, Department of Prosthodontics Dentistry, College of Dentistry, University of Baghdad Bab-Almoadham, Baghdad, Iraq

Department of Prosthodontics Dentistry, College of Dentistry, University of Baghdad Bab-Almoadham, Baghdad, Iraq

Latifa R Bairam, Department of restorative Dentistry School of Dental Medicine University of New York at Buffalo, US.

Department of restorative Dentistry School of Dental Medicine University of New York at Buffalo, US.

Zeina Al-Salihi, Department of Prosthodontics, College of Dentistry University of Iowa, S421 DSB 801 Newton Road, Iowa City, IA, US

Department of Prosthodontics, College of Dentistry University of Iowa, S421 DSB 801 Newton Road, Iowa City, IA, US

How to Cite

1.
Al-Shammari SS, Abdul-Ameer FM, Bairam LR, Al-Salihi Z. The influence of lemongrass essential oil addition into heat cured acrylic resin against Candida albicans adhesion. J Bagh Coll Dent [Internet]. 2023 Sep. 15 [cited 2024 Dec. 23];35(3):67-75. Available from: https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/3457

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