Salivary Immunoglobulin A Assessment in Lymphoma Patients before and after Chemotherapy
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Abstract
Subjects, materials and methods: The study included 25 patients (15 male and 10 female) with non–Hodgkin lymphoma(B-cell type) , 25 patients( 16 male and 9 female ) with Hodgkin lymphoma and 25 (15 male and 10 female) healthy control group. Whole un-stimulated saliva was collected to determine the level of salivary immunoglobulin A, which measured by Enzyme Link Immunosorbent Assay.
Results: The level of salivary immunoglobulin A was significantly higher in pre-treatment patients in comparison with control group, and there was a significant decrease after chemotherapy treatment when compared to their base line levels in both study groups.
Conclusion: The salivary immunoglobulin A was higher in lymphoma patients than control, then its level showed obvious decrease after chemotherapy treatment.
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