Evaluation of the Effect of Bone Morphogenetic Protein-2 on Stability of Dental Implant

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Ali Nihad,
Ali H. A. Al-Hussaini

Abstract

Background: The healing period for bone–implant contact takes 3–6 months or even longer. Application of Escherichia coli-derived recombinant human bone morphogenetic protein-2 (ErhBMP-2) to implant surfaces has been of great interest on osseointegration due to its osteoinductive potential. The objective of this study was to evaluate the effect of ErhBMP-2 on implant stability.
Materials and methods: A total of 48 dental implants were inserted in 15 patients. Twenty four implants coated with 0.5 mg/ml ErhBMP-2 (study group). The other 24 implants were uncoated (control group). Each patient was received at least two dental implants at the same session. Both groups were followed with repeated implant stability measurements by means of resonance frequency analysis at different time intervals (at the time of surgery, then at 6th and 12th week postoperatively).
Results: there was no obvious statistically significant difference in mean of implant stability quotient ISQ between study and control groups (P > 0.05) at time of surgery, whereas the mean of ISQ values at 6th and at 12th week postoperatively were statistically highly significant in the study group compared to the control group (p < 0.01).
Conclusion: The results of this study reveal that coating dental implants with ErhBMP-2 increases stability when compared with uncoated implants.

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Article Details

How to Cite
1.
Ali Nihad, A. Al-Hussaini AH. Evaluation of the Effect of Bone Morphogenetic Protein-2 on Stability of Dental Implant . J Bagh Coll Dent [Internet]. 2016 Sep. 14 [cited 2024 Mar. 29];28(3):104-9. Available from: https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/1434
Section
Oral and Maxillofacial Surgery and Periodontics

How to Cite

1.
Ali Nihad, A. Al-Hussaini AH. Evaluation of the Effect of Bone Morphogenetic Protein-2 on Stability of Dental Implant . J Bagh Coll Dent [Internet]. 2016 Sep. 14 [cited 2024 Mar. 29];28(3):104-9. Available from: https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/1434

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