Assessment Of Vascular And Lymphatic Vessels Density In Benign Vascular Lesions Using CD34 And D2-40 Immunohistochemical Markers

PDF

Published: Jun 15, 2017

DOI: https://doi.org/10.12816/0038751

Jawaher M Tater

Bashar H Abdullah

Abstract

Background: Vascular tumors and malformations, comprising a broad category of lesions often referred to as vascular anomalies. Hemangioma, represents a variety of vascular lesions (both malformations and tumor), while lobular capillary hemangioma is a common vascular lesion of the skin and mucous membranes that occurs mainly in children and young adults. Lymphangiomas are malformations of the lymphatic system. At the level of light microscopy the small lymphatics vessels may be similar to capillaries and sometimes are only tentatively identified by the nature of their contents or by immunohistochemical staining procedure. This study aimed to assess the vascular and lymphatic vessels density in benign vascular lesions using CD34 and D2-40 immunohistochemical markers.
Materials and Methods: Twenty two formalin-fixed paraffin-embedded tissue blocks of Hemangioma/vascular malformation, thirty of lobular capillary hemangioma and another twenty of lymphangioma.
Results: Lymphatic vessel density expressed by D2-40 immunomarker was found in all cases with mean (24.01Â±14.74) in lymphangioma ,for lobular capillary hemangioma it was (12.67Â±6.66) and for hemangioma was (9.77Â±6.82) where as the mean of microvessel density count measured by CD34 immunomarker was (49.87Â±31.97) for lobular capillary hemangioma , in hemangioma it was (37.42Â±23.40) and (25.90Â±12.23 ) for lymphangioma.
Conclusions: All vascular lesions are a mixture of blood and lymphatic vessels with different proportions, hemangioma shows high percentage of blood vessels and lymphangioma shows high percentage of lymphatic vessels.

Downloads

Download data is not yet available.

How to Cite

Tater JM, Abdullah BH. Assessment Of Vascular And Lymphatic Vessels Density In Benign Vascular Lesions Using CD34 And D2-40 Immunohistochemical Markers. J Bagh Coll Dent [Internet]. 2017 Jun. 15 [cited 2024 Nov. 19];29(2):61-4. Available from: https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/1862

Issue

Vol. 29 No. 2 (2017)

Section

Oral Diagnosis

Licenses and Copyright

The following policy applies in The Journal of Baghdad College of Dentistry (JBCD):

# JBCD applies the Creative Commons Attribution (CC BY) license to articles and other works we publish. If you submit your paper for publication by JBCD, you agree to have the CC BY license applied to your work. Under this Open Access license, you as the author agree that anyone can reuse your article in whole or part for any purpose, for free, even for commercial purposes. Anyone may copy, distribute, or reuse the content as long as the author and original source are properly cited. This facilitates freedom in re-use and also ensures that JBCD content can be mined without barriers for the needs of research.

# If your manuscript contains content such as photos, images, figures, tables, audio files, videos, etc., that you or your co-authors do not own, we will require you to provide us with proof that the owner of that content (a) has given you written permission to use it, and (b) has approved of the CC BY license being applied to their content. We provide a form you can use to ask for and obtain permission from the owner. If you do not have owner permission, we will ask you to remove that content and/or replace it with other content that you own or have such permission to use.Don't assume that you can use any content you find on the Internet, or that the content is fair game just because it isn't clear who the owner is or what license applies.

# Many authors assume that if they previously published a paper through another publisher, they own the rights to that content and they can freely use that content in their paper, but thatâ€™s not necessarily the case, it depends on the license that covers the other paper. Some publishers allow free and unrestricted re-use of article content they own, such as under the CC BY license. Other publishers use licenses that allow re-use only if the same license is applied by the person or publisher re-using the content. If the paper was published under a CC BY license or another license that allows free and unrestricted use, you may use the content in your JBCD paper provided that you give proper attribution, as explained above.If the content was published under a more restrictive license, you must ascertain what rights you have under that license. At a minimum, review the license to make sure you can use the content. Contact that JBCD if you have any questions about the license. If the license does not permit you to use the content in a paper that will be covered by an unrestricted license, you must obtain written permission from the publisher to use the content in your JBCD paper. Please do not include any content in your JBCD paper which you do not have rights to use, and always give proper attribution.

# If any relevant accompanying data is submitted to repositories with stated licensing policies, the policies should not be more restrictive than CC BY.

# JBCD reserves the right to remove any photos, captures, images, figures, tables, illustrations, audio and video files, and the like, from any paper, whether before or after publication, if we have reason to believe that the content was included in your paper without permission from the owner of the content.