Immunoflourescent assessment of Herpes Simplex Virus (HSV) type 1 in oral lichen planus

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Muthanna K Ali

Abstract

Background: Oral lichen planus is one of the most common dermatological diseases presenting in the oral cavity. Hence, viral infection of the oral mucosa may be involved in the pathogenesis of oral lichen planus, Taking in to consideration the oncogenic potential of HSV-1, this study aimed to assess the presence of Herpes Simplex Virus type one by direct immunoflourescent in oral lichen planus. This study aimed to assess the presence of HSV type1 by direct immunofluorescent in histopathologically diagnosed OLP
Material and Method: Twenty formalin fixed embedded tissue blocks of oral lichen planus with 2 Positive control cases were taken from patients having infection with herpes labialis, US Biological herpes simplex virus-1 Glycoprotein C was used for detection of HSV-1 Ag by direct immunofluorescence assay
Results: One case of oral lichen planus showed positivity of HSV 1 with a non- statistical significance.
Conclusion: The present study couldnt find any correlation between HSV-1 positivity with clinical and histopathological features of OLP.

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How to Cite
1.
Ali M. Immunoflourescent assessment of Herpes Simplex Virus (HSV) type 1 in oral lichen planus. JBCD [Internet]. 1 [cited 19Jun.2021];26(1):103-7. Available from: https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/305
Section
Oral Diagnosis