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Material and methods: Sixty seven formalin-fixed, paraffin-embedded tissue, histopathologically diagnosed lymphoma blocks (head and neck lesions) as (24) Hodgkinâ€™s Lymphoma and (43) Non Hodgkinâ€™s Lymphoma. Immunohistochemical (IHC) technique was used for the evaluation of P53 monoclonal antibodies expression and correlated with the clinicopathological parameters.
Results: The mean of expression of P53 in relation to tumor grades was different as it had a value of (51.2Â±13.5) in low grade tumors, (55.7Â±20) in the intermediate grade tumor and (45Â±17.6) in high grade tumors; consequently, this difference did not reached the level of statistical significance P(ANOVA) >0.05.
Conclusions: This study had shown that there was no significant correlation between the mean of expression of P53 in HL and NHL.
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