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Materials and Methods: Ninety (90) subjects were participated in this study; 45 Patients undergoing hemodialysis with chronic kidney diseases; 45 health control subjects. Saliva collected was measured and levels of salivary immunoglobulin A were measured by Enzyme Link Immunosorbent Assay (Elisa).
Results:The present studyrevealed that the mean value of salivary flow rate in chronic kidney disease patients was (0.34 Â± 0.19) ml/min, while for healthy control subjects was (1.02 Â± 0.39) ml/min, there wasstatisticallysignificantly decrease in salivary flow rate ofchronic kidney disease on hemodialysis patients as compared to control healthy subjects.The present study revealed that the (MeanÂ±SD) of the immunoglobulin A in chronic kidney disease patients on hemodialysis (388.81Â±227.86) Âµg./ml, while in control group (273.98Â±155.89) Âµg./ml, the result revealed statistically significant increase in chronic kidney disease patients on hemodialysis as compared to control subjects.
Conclusions: Salivary immunoglobulin (IgA) reflects the functional capacity of the glands. Increased concentration of this component is usually marker of a poor general condition.
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