Histological and mechanical evaluation of the osseointegration of titanium implants by the modifications of thread design and/or coating with flaxseed (An experimental study on rabbits)
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Abstract
Materials and methods: Ninety-six commercially pure titanium (CpTi) screws were implanted in rabbits' tibiae and divided into three groups as dual-threaded group, flaxseed-coated group and control group. All groups were evaluated mechanically, histologically and radiographically after each healing periods (2, 4, 6 and 8) weeks and the resulting data were statistically analyzed using ANOVA and t-test at 0.05 significance level.
Results: Dual threaded implant recorded the highest value in removal torque testand it showed mature bone at 8 weeks period. Coated implant shows enhancement of osteoblast and it is the only modified implant that illustrates proliferating cartilage zone that later on degenerated and replaced by bone.
Conclusion: Each modified implants shows different benefits whether a modification of the implant surface mechanically (dual-threaded) or by coating the implants with Flaxseed.
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