The Effect of Platelet-Rich Plasma on Osseointegration Period of Dental Implants
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Abstract
Materials and methods: A total of 28 dental implants were inserted in edentulous maxillae or mandibles of 13 patients using a split mouth design, i.e. each patient was received at least two dental implants at the same session, one implant was implanted in association with PRP which was placed locally in one site, to serve as PRP group, and the other implant was placed without PRP, to serve as a control group. Both groups were followed with repeated implant stability measurement by means of resonance frequency analysis at different time intervals (at the time of implant placement, 8th week, and 12th week postoperatively).
Results: There was no obvious statistically significant difference in mean ISQ between PRP and control groups (P > 0.05) at baseline, 8 weeks, and 12 weeks postoperatively.
Conclusions: Within the limitations of the present study, no appreciable clinical effect was observed to accelerate the rate of osseointegration of sandblasted acid-etched endosseous dental implants when using topical application of autologous PRP gel into the prepared drill holes.
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