Effect of zinc oxide nanoparticles on total salivary peroxidase activity of human saliva (In vitro study)

Main Article Content

Suha T Abd
Abbas F Ali

Abstract

Background: The potential use of zinc oxide and other metal oxide nanoparticles in biomedical are gaining interest in the scientific and medical communities, largely due to the physical and chemical properties of these nanomaterials. The present work revealed the effect of zinc oxide nanoparticles (ZnONPs) on the total salivary peroxidase enzyme activity of human saliva in comparison to de-ionized water.
Materials and methods: Forty eight unstimulated saliva samples were collected from dental students/University of Baghdad 18-22 years. Then measure the total salivary peroxidase activity first without any addition to human saliva as a control, second with dilution the saliva with de-ionized water, and third with zinc oxide nanoparticles in concentration (5.8 mg/ml).
Results: The results showed that there was significant inhibition of the activity of the total salivary peroxidase enzyme in the presence ZnO NPs and non-significant inhibition of enzyme activity in the presence de-ionized as compared with control group.
Conclusion: Zinc oxide nanoparticles have inhibition effect on total salivary peroxidase activity

Article Details

How to Cite
1.
Abd ST, Ali AF. Effect of zinc oxide nanoparticles on total salivary peroxidase activity of human saliva (In vitro study). J Bagh Coll Dent [Internet]. 2015 Jun. 15 [cited 2022 Aug. 9];27(2):178-82. Available from: https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/732
Section
Basic Sciences