The effect of age on the clinicopathological features of oral squamous cell carcinoma

Main Article Content

Alaa S Saeed
Bashar H Abdullah

Abstract

Background: Squamous cell carcinoma is a disease of elderly peopleand it is uncommon in people with less than 40 years old; however many literatures revealed that tumor developing in patients younger than forty years appears more aggressive at the time of diagnosis. The purpose of the present study was to focus on the clincopathological features of the oral SCC in different age groups. Material and methods: In this study thirty five cases of paraffin embedded tissue blocks of oral squamous cell carcinoma were studied. The age range was from 16 to 80 years. The clinicopathological data were recorded for evaluating the tumor characters according to age of patients. Results : The age was not significantly correlated to the clinicopathological features that involved the gender of the patients, anatomical site of the tumor, perineural invasion , histological grading and staging .

Downloads

Download data is not yet available.

Article Details

Section

Research Articles

How to Cite

1.
Saeed AS, Abdullah BH. The effect of age on the clinicopathological features of oral squamous cell carcinoma . J Bagh Coll Dent [Internet]. 2022 Mar. 15 [cited 2024 Dec. 27];34(1):25-8. Available from: https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/3088

References

Dascălu IT, Coleș E, Țîrcă T, et al. Histopathological aspects in oral Squamous cell carcinoma. J Dental Sci . 2018;3(2): 000173

Cassarino DS, DeRienzo DP, Barr RJ. Cutaneous squamous cell carcinoma: a comprehensive clinicopathological classification part one. J Cutan Pathol. 2006;33(3): 191-206.

Ribeiro AC, Silva AR, Simonato LE, et al. Clinical and histopathological analysis of oral squamous cell carcinoma in young people.BrJ.Oral Maxillofac. Surg.2009: 47(2) 95-98.

Muller S, Pan Y, Li R, et al. Changing trends in oral squamous cell carcinoma with particular reference to young patients: 1971–2006. The Emory University experience. Head Neck Pathol. 2008 ; 2:60-06.

Pires FR ,Ramose AB, Oliveira JB, et al. Oral squamous cell carcinoma: clinicopathological features from 346 cases from a single oral pathology service during an 8-year period. J Oral Science. 2013;21(5), 460-67.

Shiboski CH, Schmidt BL & Jordan RC. Tongue and tonsil carcinoma. J Cancer 2005; 103(9), 1843-49.

Udeabor SE, Rana M, Wegener G, et al. Squamous cell carcinoma of the oral cavity and the oropharynx in patients less than 40 years of age: a 20-year analysis. Head Neck Onco.2012;4:28-34.

Supriya NK, Srikant N, Karen B .Comparison of Clinicopathological Differences in Oral Squamous Cell Carcinoma in Patients Below and Above 40 Years of Age. J Clin. Diagnostic. Res .2017; Vol-11(9): ZC46-ZC5.

Soudry E, Preis M, Hod R, et al. Squamous cell carcinoma of the oral tongue in patients younger than 30 years: clinicopath-ologic features and outcome. Clin Otolaryngol 2010; 35(4):30712.

Santos-Silva AR, Ribeiro AC, Soubhia ,et al. High incidences of DNA ploidy abnormalities in tongue squamous cell carci-noma of young patients: an international collaborative study. Histopathology 2011;58(7):112735 .

Rushatamukayanunt P, Morita K, Matsukawa S, et al. Lack of association between high-risk human papillomaviruses and oral squamous cell carcinoma in young Japanese patients. Asian Pac J Cancer Prev. 2014; 15(10):413541.

Luan EG , Aline CB, Elismauro F , et al. Cell cycle markers and a apoptotic proteins in oral tongue squamous cell carci-noma in young and elderly patients. Braz Oral Res.2019; 33-e103.

Komolmalai N, Chuachamsai S, Tantiwipawin S ,et al. Ten year analysis of oral cancer focusing on young people in northern Thailand. J Oral Sci 2015;57(4):327-334.

Suresh T, Hemalatha A, Kumar MH, et al. Evaluation of histomorphological and immunohistochemical parameters as bi-omarkers of cervical lymph node metastasis in squamous cell carcinoma of oral cavity: A retrospective study. J. Oral Maxil-lofac. Pathol 2015; 19(1), 18.

Razavi SM & Khalesi S. Clinico-Pathological Differences of Oral Squamous Cell Carcinoma among Younger and Older Pa-tients. J Clin Exp Pathol .2017; `7: 316.

Museedi OS & Younis WH. Oral cancer trends in Iraq from 2000 to 2008. Saudi J.Dent.Res.2014; 5(1), 41-47.

Syedmukith R, Ahmedmujib BR, Bastian TS. Oral Squamous Cell Carcinoma in Elderly vs Young Patients: A Comparative Analysis using STNMP StagingSystem. J OralMaxillofac. Pathol 2014;5(2):471-475.

Sasaki T, Moles DR, Imai Y, et al. Clinico-pathological features of squamous cell carcinoma of the oral cavity in patients <40 years of age. J Oral Pathol Med. 2005;34:129-33.

Iype EM, Pandey M, Mathew A, et al. Oral cancer among patients under the age of 35 years. J Postgrad Med.2001; 47(3):171-176.

Shuwei C, Zhu L, Jingtao C , et al . Older age is a risk factor associated with poor prognosis of patients with squamous cell carcinoma of the oral cavity European Archive of Oto-Rhino-Laryngology.2020 ; 277:2573–2580.

Zhang YY, Wang DC, Su JJ et al. Clinicopathological characteristics and outcomes of squamous cell carcinoma of the tongue in different age groups. Head& Neck 2017;39: 2276-82.

Gyuheon C, Joon S, Seung HC et al. Comparison of Squamous Cell Carcinoma of the Tongue Between Young and Old Pa-tients, Seoul, Korea .J Patho Transl Med.2019;53(6).

Similar Articles

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)