Clinicopathological assessment of chronic hyperplastic candidasis

Main Article Content

Hussain S Hussain
Ban F Al-Drobie

Abstract

Background: Chronic hyperplastic candidiasis is the least common type of oral candidiasis. The diagnosis, long-term treatment, and prognosis of this potentially malignant oral condition are still currently unclear. Objective: the aim of this study is to analyze the demographic features and clinical characteristics of oral chronic hyperplastic candidiasis. Materials and Methods: A retrospective analysis was performed on blocks and case sheets of patients who were diagnosed with chronic hyperplastic candidiasis in the archives of Oral and Maxillofacial Pathology at the College of Dentistry/University of Baghdad. Demographic and clinical characteristics were analyzed. Results: twenty-one cases with chronic hyperplastic candidiasis were collected and reviewed. Buccal mucosa was the most affected sites. Regarding the clinical features, lesions color frequently presented as white plaque. Regarding clinical diagnosis, leukoplakia was noted the highest one among other previous diagnosis. Conclusions: Older adults are the mostly affected age group by chronic hyperplastic candidiasis with slight male predilection. White plaque is the most presented clinical feature with buccal mucosa being the most affected oral site.

Downloads

Download data is not yet available.

Article Details

Section

Research Articles

How to Cite

1.
Hussain HS, Al-Drobie BF. Clinicopathological assessment of chronic hyperplastic candidasis. J Bagh Coll Dent [Internet]. 2022 Dec. 15 [cited 2024 Dec. 24];34(4):28-33. Available from: https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/3274

References

Krishnan, P. A. (2012). Fungal infections of the oral mucosa. Indian journal of dental research, 23(5), 650.

Hellstein, J. W., and Marek, C. L. (2019). Candidiasis: red and white manifestations in the oral cavity. Head and neck Pathology, 13(1), 25-32

Hu, L., Zhou, P., Zhao, W., Hua, H., & Yan, Z. (2020). Fluorescence staining vs. routine KOH smear for rapid diagnosis of oral candidiasis—A diagnostic test. Oral diseases, 26(5), 941-947.

Shah, N., Ray, J. G., Kundu, S., & Sardana, D. (2017). Surgical management of chronic hyperplastic candidiasis refractory to systemic antifungal treatment. Journal of Laboratory Physicians, 9(02), 136-139.

Telles, D. R., Karki, N., & Marshall, M. W. (2017). Oral fungal infections: diagnosis and management. Dental Clinics, 61(2), 319-349.

Sitheeque, M., & Samaranayake, L. (2003). Chronic hyperplastic candidosis/candidiasis (candidal leukoplakia). Critical Reviews in Oral Biology & Medicine, 14(4), 253-267.

Bartie, K. L., Williams, D. W., Wilson, M., Potts, A. J. C., & Lewis, M. A. O. (2004). Differential invasion of Candida albicans isolates in an in vitro model of oral candidosis. Oral microbiology and immunology, 19(5), 293-296.

Holmstrup, P., Vedtofte, P., Reibel, J., & Stoltze, K. (2006). Long-term treatment outcome of oral premalignant lesions. Oral oncology, 42(5), 461-474.

Akpan, A., & Morgan, R. (2002). Oral candidiasis. Postgraduate medical journal, 78(922), 455-459.

Sharma, A. (2019). Oral candidiasis: An opportunistic infection: A review. Int J Applied Dent Sci, 5(1), 23-27

Kim, J., and Sudbery, P. (2011). Candida albicans, a major human fungal pathogen. The Journal of Microbiology, 49(2), 171-177

Lott, T. J., Fundyga, R. E., Kuykendall, R. J., and Arnold, J. (2005). The human commensal yeast, Candida albicans, has an ancient origin. Fungal Genetics and Biology, 42(5), 444-451

Oliver, D. t., & Shillitoe, E. (1984). Effects of smoking on the prevalence and intraoral distribution of Candida albicans. Journal of Oral Pathology & Medicine, 13(3), 265¬270.

Warnakulasuriya, S., Johnson, N. W., & Van der Waal, I. (2007). Nomenclature and classification of potentially malignant disorders of the oral mucosa. Journal of oral pathology & medicine, 36(10), 575-580.‏

Warnakulasuriya, S., & Ariyawardana, A. (2016). Malignant transformation of oral leukoplakia: a systematic review of observational studies. Journal of Oral Pathology & Medicine, 45(3

Similar Articles

You may also start an advanced similarity search for this article.